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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Sammy Sosa | 576 | 1989-2007 | |
| 1 | Giancarlo Stanton* | 576 | 2010-2030 | |
| 3 | Hank Aaron* | 534 | 1954-1976 | |
| 4 | Babe Ruth* | 518 | 1914-1935 | |
| 5 | Danny Delgado* | 504 | 2071-2090 | |
| 6 | Reggie Jackson* | 465 | 1967-1987 | |
| 7 | Mel Ott* | 445 | 1926-1947 | |
| 8 | Isaiah Williams# | 434 | 2088-2098 | |
| 9 | Eric Cartwright | 418 | 2059-2077 | |
| 10 | Jose Valdez | 397 | 2023-2035 | |
| 11 | Jeff Cinnamon# | 394 | 2086-2098 | |
| 12 | Vladimir Guerrero* | 392 | 1996-2011 | |
| 13 | Alex Gonzalez | 390 | 2037-2051 | |
| 14 | Pedro Limon | 387 | 2044-2061 | |
| 15 | Tim Rider | 377 | 2059-2070 | |
| 16 | Oscar Nieves* | 371 | 2030-2048 | |
| 17 | Larry Walker | 365 | 1989-2005 | |
| 18 | Oscar Casas | 356 | 2068-2080 | |
| 19 | Diego Somarriba* | 353 | 2028-2048 | |
| 20 | Kyle Rolland | 351 | 2060-2072 | |
| 21 | Jonathan Arvizo* | 350 | 2041-2057 | |
| 22 | Dwight Evans | 337 | 1972-1991 | |
| 23 | Frank Robinson* | 336 | 1956-1976 | |
| 24 | Jason Christ | 327 | 2063-2075 | |
| 24 | Francisco Perez | 327 | 2025-2042 | |
| 26 | Jermaine Dye | 325 | 1996-2009 | |
| 27 | Austin Biggs | 322 | 2044-2058 | |
| 28 | Bobby Bonds | 321 | 1968-1981 | |
| 29 | Edwin Ortiz | 318 | 2038-2050 | |
| 30 | Kirk Lykins | 315 | 2039-2050 | |
| 31 | Bryan Boucher | 308 | 2084-2094 | |
| 31 | Jay Buhner | 308 | 1987-2001 | |
| 31 | Edgar Rosario | 308 | 2050-2063 | |
| 34 | Jose Bautista | 307 | 2004-2019 | |
| 35 | Dave Winfield* | 301 | 1973-1995 | |
| 36 | Shawn Green | 300 | 1993-2007 | |
| 37 | Al Kaline* | 296 | 1953-1974 | |
| 37 | Sean Schwenk | 296 | 2070-2083 | |
| 39 | Magglio Ordonez | 294 | 1997-2011 | |
| 39 | Darryl Strawberry | 294 | 1983-1999 | |
| 41 | Matthew Ochs | 289 | 2083-2096 | |
| 41 | Jorge Soler | 289 | 2014-2029 | |
| 43 | Bryce Harper* | 288 | 2012-2032 | |
| 44 | Jeromy Burnitz | 284 | 1993-2006 | |
| 44 | Miguel Gonzalez* | 284 | 2054-2068 | |
| 46 | Paul O'Neill | 281 | 1985-2001 | |
| 47 | Bobby Abreu | 277 | 1996-2014 | |
| 48 | Jesse Ebert* | 273 | 2056-2073 | |
| 48 | Dave Parker | 273 | 1973-1991 | |
| 50 | Rocky Colavito | 270 | 1955-1968 | |
| 50 | Gustavo Saro | 270 | 2076-2090 | |
| 52 | Tom Brunansky | 268 | 1981-1994 | |
| 52 | Mark Menard | 268 | 2043-2054 | |
| 52 | Gary Sheffield | 268 | 1988-2009 | |
| 55 | Josh Ingram | 266 | 2075-2087 | |
| 56 | Michael Raybon | 264 | 2069-2086 | |
| 57 | Aaron Judge | 262 | 2016-2028 | |
| 57 | Tim Salmon | 262 | 1992-2006 | |
| 59 | Roger Maris | 261 | 1957-1968 | |
| 59 | Brendan Wallace | 261 | 2055-2066 | |
| 61 | Javier Millan | 260 | 2069-2080 | |
| 62 | Kyle Tucker | 254 | 2017-2035 | |
| 63 | Paul Hollinger | 252 | 2042-2053 | |
| 64 | Chuck Klein* | 249 | 1928-1944 | |
| 65 | Hector Diaz | 248 | 2053-2065 | |
| 66 | Josh Bernier | 247 | 2026-2035 | |
| 67 | Bobby Mora | 244 | 2081-2089 | |
| 67 | Oiva Niiranen | 244 | 2078-2093 | |
| 69 | Andre Dawson* | 242 | 1976-1996 | |
| 70 | Jesse Barfield | 241 | 1981-1992 | |
| 71 | Jay Bruce | 240 | 2008-2018 | |
| 71 | Roberto Clemente* | 240 | 1955-1972 | |
| 73 | Dustin van der Schoot | 238 | 2048-2064 | |
| 74 | Paço Bagrro | 235 | 2070-2084 | |
| 74 | Bill Nicholson | 235 | 1936-1953 | |
| 76 | Jason Marmon | 234 | 2064-2077 | |
| 76 | Raul Mondesi | 234 | 1993-2005 | |
| 76 | Manny Ramirez* | 234 | 1993-2011 | |
| 79 | Jose Cruz | 231 | 2066-2078 | |
| 79 | Yazid Deacon# | 231 | 2088-2098 | |
| 79 | Mang Zhang | 231 | 2044-2055 | |
| 82 | Steve Gumaer | 230 | 2048-2060 | |
| 83 | Hunter Pence | 229 | 2007-2020 | |
| 84 | Luis Leyva | 227 | 2073-2086 | |
| 85 | Juan Gonzalez | 225 | 1989-2005 | |
| 85 | Jose Motta | 225 | 2039-2049 | |
| 87 | J.D. Drew | 224 | 1998-2011 | |
| 87 | Ruben Sierra | 224 | 1986-2006 | |
| 89 | Kevin Luzzo# | 221 | 2089-2098 | |
| 90 | Richard Segur | 219 | 2057-2067 | |
| 91 | John Quail | 218 | 2056-2065 | |
| 91 | Reggie Sanders | 218 | 1991-2007 | |
| 93 | Arturo Coranillo | 214 | 2053-2065 | |
| 93 | Brandon Henson | 214 | 2024-2038 | |
| 93 | Scott Jansen | 214 | 2065-2075 | |
| 96 | Jonas Belles | 213 | 2037-2045 | |
| 96 | Johnny Callison | 213 | 1958-1973 | |
| 96 | Heriberto Mendoza# | 213 | 2084-2097 | |
| 99 | Orlando Juarez | 207 | 2059-2068 | |
| 100 | Danny Gregory | 206 | 2044-2057 |
