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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | RBI | YEAR | Open Career Leaderboard |
|---|---|---|---|---|
| 1 | Lou Gehrig* | 184 | 1931 | |
| 2 | Hank Greenberg* | 183 | 1937 | |
| 3 | Jimmie Foxx* | 175 | 1938 | |
| 3 | Lou Gehrig* | 175 | 1927 | |
| 5 | Lou Gehrig* | 174 | 1930 | |
| 6 | Wayne Paris* | 173 | 2077 | |
| 7 | Hank Greenberg* | 170 | 1935 | |
| 8 | Jimmie Foxx* | 169 | 1932 | |
| 9 | Rodolfo Barbosa | 168 | 2065 | |
| 10 | Wayne Paris* | 165 | 2076 | |
| 10 | Lou Gehrig* | 165 | 1934 | |
| 12 | Jimmie Foxx* | 163 | 1933 | |
| 13 | Hal Trosky | 162 | 1936 | |
| 14 | Rich Gonzales* | 160 | 2052 | |
| 14 | Bruce Grimes* | 160 | 2046 | |
| 16 | Dave Valdivia | 159 | 2076 | |
| 16 | Lou Gehrig* | 159 | 1937 | |
| 16 | John Conway# | 159 | 2091 | |
| 19 | Jimmie Foxx* | 156 | 1930 | |
| 20 | Joe Keller* | 155 | 2062 | |
| 21 | Juan Valentin* | 154 | 2079 | |
| 22 | Javier Serrato* | 153 | 2038 | |
| 23 | Lou Gehrig* | 152 | 1936 | |
| 24 | Joe Keller* | 151 | 2064 | |
| 24 | Ben Thomas* | 151 | 2072 | |
| 24 | Lou Gehrig* | 151 | 1932 | |
| 24 | Chris Wright# | 151 | 2088 | |
| 28 | Wayne Paris* | 150 | 2079 | |
| 28 | Doug MacFarlan | 150 | 2040 | |
| 28 | Andres Galarraga | 150 | 1996 | |
| 28 | Santiago Bernabe | 150 | 2064 | |
| 32 | Ryan Howard | 149 | 2006 | |
| 32 | Miguel Sano | 149 | 2020 | |
| 32 | Wayne Paris* | 149 | 2078 | |
| 35 | Doug MacFarlan | 148 | 2047 | |
| 35 | Victor Gutierrez | 148 | 2083 | |
| 37 | Juan Valentin* | 147 | 2081 | |
| 37 | Mark McGwire | 147 | 1998 | |
| 37 | Cap Anson* | 147 | 1886 | |
| 37 | John Conway# | 147 | 2092 | |
| 37 | Mark McGwire | 147 | 1999 | |
| 37 | Todd Helton* | 147 | 2000 | |
| 43 | Wayne Paris* | 146 | 2073 | |
| 43 | Hank Greenberg* | 146 | 1938 | |
| 43 | Ramon Carrion# | 146 | 2096 | |
| 43 | Joe Keller* | 146 | 2061 | |
| 43 | Ryan Howard | 146 | 2008 | |
| 43 | Todd Helton* | 146 | 2001 | |
| 49 | Carlos Delgado | 145 | 2003 | |
| 49 | Don Mattingly | 145 | 1985 | |
| 49 | Josh Thomas | 145 | 2034 | |
| 49 | Sam Hicks | 145 | 2040 | |
| 49 | Steve Casarez | 145 | 2073 | |
| 54 | Mark Teixeira | 144 | 2005 | |
| 54 | Juan Valentin* | 144 | 2080 | |
| 54 | Javier Serrato* | 144 | 2028 | |
| 54 | Walt Dropo | 144 | 1950 | |
| 54 | Mike Sweeney | 144 | 2000 | |
| 54 | Javier Serrato* | 144 | 2037 | |
| 60 | Mo Vaughn | 143 | 1996 | |
| 60 | Javier Serrato* | 143 | 2029 | |
| 60 | Bob Rogers | 143 | 2077 | |
| 60 | Chris Benitez* | 143 | 2082 | |
| 60 | Julio Huaman | 143 | 2037 | |
| 60 | Jimmie Foxx* | 143 | 1936 | |
| 60 | Don Hurst | 143 | 1932 | |
| 67 | Orlando Cepeda* | 142 | 1961 | |
| 67 | Hal Trosky | 142 | 1934 | |
| 67 | Rich Gonzales* | 142 | 2050 | |
| 67 | Alex Esquibel* | 142 | 2027 | |
| 67 | Rafael Palmeiro | 142 | 1996 | |
| 67 | Franklin Correa | 142 | 2058 | |
| 67 | Doug MacFarlan | 142 | 2045 | |
| 67 | Lou Gehrig* | 142 | 1928 | |
| 67 | Javier Serrato* | 142 | 2031 | |
| 76 | Pedro Porras# | 141 | 2090 | |
| 76 | Jim Gentile | 141 | 1961 | |
| 76 | Prince Fielder* | 141 | 2009 | |
| 76 | Ted Kluszewski | 141 | 1954 | |
| 76 | Tino Martinez | 141 | 1997 | |
| 76 | Ryan Howard | 141 | 2009 | |
| 82 | Sam Hicks | 140 | 2043 | |
| 82 | Andres Galarraga | 140 | 1997 | |
| 84 | Hank Greenberg* | 139 | 1934 | |
| 84 | Jim Kimble* | 139 | 2080 | |
| 84 | Mario Plata | 139 | 2049 | |
| 84 | Lou Gehrig* | 139 | 1933 | |
| 84 | Sam Hicks | 139 | 2042 | |
| 84 | Kurt Adams | 139 | 2072 | |
| 84 | Javier Serrato* | 139 | 2032 | |
| 84 | Juan Ortiz | 139 | 2067 | |
| 92 | Johnny Mize* | 138 | 1947 | |
| 92 | Wayne Paris* | 138 | 2072 | |
| 92 | Jamie Hantke | 138 | 2085 | |
| 92 | Zeke Bonura | 138 | 1936 | |
| 92 | Chris Davis | 138 | 2013 | |
| 92 | Alfredo Sanchez | 138 | 2031 | |
| 92 | Jose Restrepo | 138 | 2059 | |
| 92 | Miguel Andujar* | 138 | 2027 | |
| 100 | Miguel Andujar* | 137 | 2028 |
