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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | RBI | YEAR | Open Career Leaderboard |
|---|---|---|---|---|
| 1 | Babe Ruth* | 171 | 1921 | |
| 2 | Al Simmons* | 165 | 1930 | |
| 3 | Ted Williams* | 159 | 1949 | |
| 4 | Al Simmons* | 157 | 1929 | |
| 4 | Jose Vargas | 157 | 2066 | |
| 6 | Ken Williams | 155 | 1922 | |
| 7 | Joe Medwick* | 154 | 1937 | |
| 8 | Tommy Davis | 153 | 1962 | |
| 9 | Nick Maifeld* | 152 | 2047 | |
| 9 | Ryan Humel | 152 | 2046 | |
| 9 | Albert Belle | 152 | 1998 | |
| 12 | David Doss | 151 | 2084 | |
| 12 | Dan Barnett* | 151 | 2070 | |
| 12 | Al Simmons* | 151 | 1932 | |
| 15 | Babe Ruth* | 150 | 1926 | |
| 15 | Hank Greenberg* | 150 | 1940 | |
| 15 | Peter Adams* | 150 | 2043 | |
| 18 | George Foster | 149 | 1977 | |
| 19 | Albert Belle | 148 | 1996 | |
| 19 | Dan Barnett* | 148 | 2071 | |
| 21 | Ed Delahanty* | 146 | 1893 | |
| 21 | Chris Haffey# | 146 | 2087 | |
| 21 | Chris Haffey# | 146 | 2091 | |
| 21 | Nick Maifeld* | 146 | 2046 | |
| 25 | Manny Ramirez* | 144 | 2005 | |
| 25 | Tony Merkin | 144 | 2086 | |
| 27 | Ryan Humel | 142 | 2047 | |
| 27 | Luis Gonzalez | 142 | 2001 | |
| 29 | Dan Barnett* | 140 | 2077 | |
| 29 | Rocky Colavito | 140 | 1961 | |
| 29 | Daniel Tellado | 140 | 2087 | |
| 32 | Jim Rice* | 139 | 1978 | |
| 32 | Jon Young# | 139 | 2098 | |
| 32 | Don Baylor | 139 | 1979 | |
| 35 | Joe Medwick* | 138 | 1936 | |
| 35 | Ryan Humel | 138 | 2044 | |
| 35 | Bob Meusel | 138 | 1925 | |
| 35 | Sergio Arreola* | 138 | 2072 | |
| 35 | Goose Goslin* | 138 | 1930 | |
| 35 | Todd Lowry | 138 | 2077 | |
| 41 | Ted Williams* | 137 | 1942 | |
| 41 | Ed Delahanty* | 137 | 1899 | |
| 41 | Peter Adams* | 137 | 2046 | |
| 41 | Barry Bonds | 137 | 2001 | |
| 41 | Matt Holliday | 137 | 2007 | |
| 41 | Luis Ruiz* | 137 | 2058 | |
| 47 | Ryan Humel | 135 | 2043 | |
| 47 | Dan Owen | 135 | 2057 | |
| 49 | George Bell | 134 | 1987 | |
| 49 | Han-seung Kwon | 134 | 2024 | |
| 49 | Tom Ellis* | 134 | 2029 | |
| 49 | Chris Haffey# | 134 | 2088 | |
| 49 | Elijah Fairchild# | 134 | 2095 | |
| 49 | Moose Solters | 134 | 1936 | |
| 49 | Eric Cartwright | 134 | 2066 | |
| 56 | Heriberto Mendoza# | 133 | 2092 | |
| 56 | Peter Adams* | 133 | 2044 | |
| 56 | Tom Ellis* | 133 | 2028 | |
| 56 | Steve Curtner | 133 | 2043 | |
| 56 | Luis Ruiz* | 133 | 2060 | |
| 56 | Dante Bichette | 133 | 1999 | |
| 56 | Nick Maifeld* | 133 | 2049 | |
| 56 | Luis Ruiz* | 133 | 2059 | |
| 64 | Irish Meusel | 132 | 1922 | |
| 65 | Ed Delahanty* | 131 | 1894 | |
| 65 | Jason Guzzi# | 131 | 2088 | |
| 65 | Joe Hall | 131 | 2037 | |
| 65 | Dan Barnett* | 131 | 2072 | |
| 69 | Walt Wilmot | 130 | 1894 | |
| 69 | Manny Ramirez* | 130 | 2004 | |
| 69 | Jim Rice* | 130 | 1979 | |
| 69 | Kevin Durham | 130 | 2079 | |
| 69 | Greg Luzinski | 130 | 1977 | |
| 74 | Barry Bonds | 129 | 1996 | |
| 74 | Gus Zernial | 129 | 1951 | |
| 74 | Billy Williams* | 129 | 1970 | |
| 74 | Goose Goslin* | 129 | 1924 | |
| 74 | Chris Haffey# | 129 | 2086 | |
| 74 | Hugh Duffy* | 129 | 1897 | |
| 74 | Albert Belle | 129 | 1993 | |
| 74 | Luis Ruiz* | 129 | 2057 | |
| 74 | Dan Barnett* | 129 | 2076 | |
| 83 | Dante Bichette | 128 | 1995 | |
| 83 | Al Simmons* | 128 | 1931 | |
| 83 | Peter Adams* | 128 | 2041 | |
| 83 | Ellis Burks | 128 | 1996 | |
| 83 | Bobby Veach | 128 | 1921 | |
| 88 | Jason Guzzi# | 127 | 2089 | |
| 88 | Ralph Kiner* | 127 | 1949 | |
| 88 | Elijah Fairchild# | 127 | 2091 | |
| 88 | Albert Pujols* | 127 | 2002 | |
| 88 | Chris Short | 127 | 2060 | |
| 88 | Todd Lowry | 127 | 2076 | |
| 88 | Ted Williams* | 127 | 1948 | |
| 88 | Kevin Durham | 127 | 2078 | |
| 88 | Ralph Kiner* | 127 | 1947 | |
| 88 | Larry Wilson | 127 | 2061 | |
| 98 | Frank Howard | 126 | 1970 | |
| 98 | Ed Delahanty* | 126 | 1896 | |
| 98 | Joe Medwick* | 126 | 1935 |
