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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Lorenzo Claudio | 43 | 2067-2071 | |
| 2 | Alex Garza | 35 | 2054-2057 | |
| 3 | William Edwards | 28 | 2046-2046 | |
| 4 | Eric Graham | 27 | 2069-2070 | |
| 4 | Jonathan Sharpe | 27 | 2068-2069 | |
| 6 | Chris Fox | 26 | 2028-2029 | |
| 7 | Omari Smith | 25 | 2076-2077 | |
| 7 | Jose Velasco | 25 | 2083-2084 | |
| 9 | Jacob Chivers | 24 | 2063-2063 | |
| 10 | JaCoby Jones | 23 | 2014-2014 | |
| 11 | Jon Bonilla | 22 | 2072-2072 | |
| 11 | Antonio Cruz | 22 | 2055-2058 | |
| 13 | Leon Chavez | 20 | 2021-2021 | |
| 13 | Ryan Taylor# | 20 | 2090-2091 | |
| 15 | Pat Garner | 19 | 2068-2069 | |
| 15 | Matt Hoffman | 19 | 2083-2084 | |
| 15 | Jake Laverty | 19 | 2048-2049 | |
| 15 | Ryan Mountcastle | 19 | 2016-2016 | |
| 15 | Josh Patton | 19 | 2083-2084 | |
| 20 | Leo Aguila | 18 | 2061-2062 | |
| 20 | Elijah Harris | 18 | 2060-2061 | |
| 20 | Erik Martin | 18 | 2049-2049 | |
| 20 | Trevor Story | 18 | 2012-2012 | |
| 20 | Jorge Zavala | 18 | 2061-2061 | |
| 25 | John Carr# | 17 | 2091-2094 | |
| 25 | Aaron Jones | 17 | 2049-2049 | |
| 25 | Victor Velez | 17 | 2039-2040 | |
| 28 | Xander Bogaerts | 16 | 2011-2011 | |
| 28 | Ti'Quan Forbes | 16 | 2016-2017 | |
| 28 | Alen Hanson | 16 | 2012-2012 | |
| 28 | Rosell Herrera | 16 | 2012-2013 | |
| 28 | Adam Scruggs | 16 | 2032-2034 | |
| 28 | Kris Soto | 16 | 2056-2056 | |
| 28 | Kyle Spencer# | 16 | 2095-2096 | |
| 28 | Cesar Valenzuela | 16 | 2072-2073 | |
| 36 | Roberto Fallas# | 15 | 2094-2094 | |
| 36 | Javier Guerra | 15 | 2015-2015 | |
| 36 | Doug Pace | 15 | 2064-2064 | |
| 36 | Joey Rohleder | 15 | 2041-2041 | |
| 40 | Bobby Castillo# | 14 | 2090-2092 | |
| 40 | Wilmer Difo | 14 | 2013-2014 | |
| 40 | Jonathan Howell | 14 | 2075-2075 | |
| 40 | Adam Hubbard | 14 | 2041-2042 | |
| 40 | T.J. McClain | 14 | 2064-2065 | |
| 40 | Justin Mielke | 14 | 2036-2037 | |
| 40 | John Mims | 14 | 2033-2033 | |
| 40 | Chris Nelson | 14 | 2005-2006 | |
| 48 | Danny Abril | 13 | 2039-2039 | |
| 48 | Chris Brennan | 13 | 2082-2082 | |
| 48 | Aaron Comeaux# | 13 | 2087-2088 | |
| 48 | Craig Dennison# | 13 | 2094-2098 | |
| 48 | Josh Harold | 13 | 2030-2031 | |
| 48 | Ryan Takach# | 13 | 2094-2096 | |
| 48 | Justin Twine | 13 | 2015-2016 | |
| 48 | Jeremy Workman | 13 | 2066-2067 | |
| 56 | Mort Akers | 12 | 2047-2047 | |
| 56 | Chris Elliott | 12 | 2052-2053 | |
| 56 | Matt Gomez | 12 | 2067-2068 | |
| 56 | Tristan Hughes | 12 | 2027-2027 | |
| 56 | Emerson Jimenez | 12 | 2014-2016 | |
| 56 | Kyle Kurtz# | 12 | 2092-2092 | |
| 56 | Ramon Mesa | 12 | 2053-2053 | |
| 56 | Jonathan Moreno | 12 | 2085-2090 | |
| 56 | Bill Nichols | 12 | 2052-2052 | |
| 56 | Dave Prieto | 12 | 2088-2090 | |
| 56 | Jurickson Profar | 12 | 2011-2015 | |
| 56 | Jordan Ramos | 12 | 2031-2033 | |
| 56 | Chris Sims# | 12 | 2091-2091 | |
| 56 | John Stevens# | 12 | 2094-2095 | |
| 70 | Darnell Calhoun | 11 | 2077-2078 | |
| 70 | Javier Casanova | 11 | 2086-2086 | |
| 70 | Jose Chavarria# | 11 | 2087-2087 | |
| 70 | Sergio Cortez | 11 | 2090-2091 | |
| 70 | Jason Cox | 11 | 2030-2030 | |
| 70 | Ramon Flores | 11 | 2025-2025 | |
| 70 | Ethan Harvey | 11 | 2028-2029 | |
| 70 | Dave Lutz | 11 | 2027-2029 | |
| 70 | Crispino Pastorelli# | 11 | 2094-2095 | |
| 70 | Stephen Shaffer | 11 | 2059-2059 | |
| 70 | Mike Thomas | 11 | 2073-2074 | |
| 70 | Matt Weaver# | 11 | 2090-2090 | |
| 70 | Matt Whitfield | 11 | 2085-2086 | |
| 70 | Jonathan Williams | 11 | 2073-2073 | |
| 84 | Mike Bird | 10 | 2069-2070 | |
| 84 | Cito Culver | 10 | 2012-2013 | |
| 84 | Tim DeVries | 10 | 2082-2084 | |
| 84 | Wilmer Flores | 10 | 2008-2010 | |
| 84 | Jesus Garcia | 10 | 2084-2086 | |
| 84 | Tim Gatti# | 10 | 2094-2094 | |
| 84 | Tien Dung Luu | 10 | 2065-2066 | |
| 84 | Mike McElroy | 10 | 2061-2062 | |
| 84 | Justin Teufel# | 10 | 2098-2098 | |
| 93 | Keith Aschbrenner | 9 | 2035-2035 | |
| 93 | Dylan Bohnert | 9 | 2018-2020 | |
| 93 | Andy Daniel | 9 | 2043-2043 | |
| 93 | Randy Edwards | 9 | 2036-2036 | |
| 93 | Bobby Gatlin | 9 | 2054-2054 | |
| 93 | Mike Hancock# | 9 | 2088-2088 | |
| 93 | John Harris | 9 | 2055-2055 | |
| 93 | Pat Houdek | 9 | 2083-2084 |
