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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sabatino, Bobby | RP | Mobile BayBears | 25 | 11/11/2085 | Lewiston | USA | Right | Right | 6' 3" | 200 lbs | - |
| Salgado, Jose | RF | Free Agent | 27 | 08/27/2083 | Catacamas | HON | Left | Left | 6' 3" | 200 lbs | - |
| Saltzman, Dan | SP | Mississippi Braves | 26 | 01/30/2085 | San Diego | USA | Right | Right | 6' 1" | 185 lbs | - |
| Sanchez, Luis | SP | Pensacola Blue Wahoos | 24 | 12/22/2086 | Santo Domingo | DOM | Left | Left | 6' 5" | 200 lbs | - |
| Sandoval, Manny | SP | Free Agent | 31 | 06/28/2079 | El Limón | VEN | Right | Right | 6' 1" | 195 lbs | - |
| Santana, Basilio | LF | Free Agent | 28 | 05/12/2082 | Machiques | VEN | Switch | Right | 6' 1" | 200 lbs | - |
| Santana, Sal | LF | Montgomery Biscuits | 22 | 02/28/2088 | Ponce | PUR | Left | Left | 6' 2" | 200 lbs | - |
| Saray, Hector | RP | Biloxi Shuckers | 25 | 01/26/2086 | Maracaibo | VEN | Right | Right | 6' 2" | 195 lbs | - |
| Savage, Dan | 3B | Jacksonville Suns | 23 | 06/11/2087 | New York | USA | Switch | Right | 6' 4" | 200 lbs | - |
| Scallini, Tony | 3B | Biloxi Shuckers | 24 | 09/18/2086 | Acarigua | VEN | Right | Right | 6' 2" | 200 lbs | - |
| Scott, Aaron | SP | Free Agent | 25 | 02/20/2085 | New York | USA | Right | Right | 6' 7" | 200 lbs | - |
| Segovia, Bobby | SP | Pensacola Blue Wahoos | 24 | 11/25/2086 | Franconia | USA | Left | Right | 6' 3" | 200 lbs | - |
| Selfridge, Nick | LF | Birmingham Barons | 23 | 06/17/2087 | Miami Gardens | USA | Right | Right | 6' 3" | 195 lbs | - |
| Shaw, Jesse | C | Biloxi Shuckers | 22 | 07/11/2088 | Spanish Lake | USA | Right | Right | 6' 2" | 195 lbs | - |
| Shelton, Jim | C | Mobile BayBears | 24 | 02/14/2086 | Grand Prairie | USA | Right | Right | 6' 0" | 195 lbs | - |
| Sierra, Luis | RP | Free Agent | 25 | 11/18/2085 | Santo Domingo | DOM | Switch | Left | 6' 2" | 195 lbs | - |
| Silguero, Willis | RP | Jackson Generals | 22 | 03/16/2088 | Piedras Negras | MEX | Right | Right | 6' 3" | 195 lbs | - |
| Silva, Alfredo | RP | Birmingham Barons | 25 | 03/16/2085 | Santo Domingo | DOM | Right | Right | 6' 1" | 200 lbs | - |
| Silva, Ramon | SP | Free Agent | 26 | 05/20/2084 | Nagua | DOM | Right | Right | 6' 2" | 190 lbs | - |
| Simple, Sean | C | Pensacola Blue Wahoos | 23 | 09/04/2087 | El Dorado | USA | Switch | Right | 6' 3" | 200 lbs | - |
| Sloan, Mike | 2B | Mississippi Braves | 26 | 03/03/2084 | West Side Highway | USA | Right | Right | 6' 1" | 200 lbs | - |
| Spalinger, Ryan | CF | Mississippi Braves | 22 | 08/10/2088 | Racine | USA | Right | Right | 6' 1" | 185 lbs | - |
| Sparkman, Matt | C | Jackson Generals | 25 | 10/19/2085 | Woodhaven | USA | Right | Right | 6' 4" | 200 lbs | - |
| Starks, Tim | C | Birmingham Barons | 25 | 04/13/2085 | Salt Lake City | USA | Right | Right | 6' 1" | 200 lbs | - |
| Starnes, Tommy | CF | Montgomery Biscuits | 23 | 01/07/2088 | Hampton Township | USA | Right | Right | 6' 2" | 175 lbs | - |
| Steens, Daniel | 1B | Free Agent | 26 | 04/15/2084 | Lochem | NED | Switch | Right | 6' 2" | 200 lbs | - |
| Stember, Andy | SP | Tennessee Smokies | 25 | 05/25/2085 | China Grove | USA | Left | Left | 6' 2" | 200 lbs | - |
| Stephens, Tim | CL | Birmingham Barons | 26 | 02/05/2084 | Corcoran | USA | Right | Right | 6' 1" | 200 lbs | - |
| Stinnett, Jake | RP | Montgomery Biscuits | 23 | 10/05/2087 | Los Angeles | USA | Left | Left | 6' 3" | 185 lbs | - |
| Suazo, Jordan | RF | Montgomery Biscuits | 23 | 05/03/2087 | Riverhead | USA | Left | Left | 5' 11" | 185 lbs | - |
| Sullens, Jon | CF | Free Agent | 25 | 12/31/2085 | Kenilworth | USA | Right | Right | 6' 2" | 200 lbs | - |
| Supico, Tobias | CF | Mississippi Braves | 23 | 05/02/2087 | Puerto la Cruz | VEN | Switch | Right | 6' 2" | 185 lbs | - |
