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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sabala, Dave | RP | Bluefield Blue Jays | 21 | 03/10/2090 | Santiago | DOM | Right | Right | 5' 11" | 175 lbs | - |
| Saidel, Chris | CF | Bluefield Blue Jays | 22 | 10/02/2088 | Saybrook Manor | USA | Right | Right | 6' 0" | 190 lbs | - |
| Salcedo, Octavio | RP | San Diego (Rk+) Padres | 21 | 01/29/2090 | Woodridge | USA | Switch | Right | 6' 9" | 205 lbs | - |
| Saldana, Jordan | SP | Baltimore (Rk+) Orioles | 19 | 11/18/2091 | Mérida | VEN | Right | Right | 6' 2" | 180 lbs | - |
| Sanabria, Humberto | SS | Princeton Rays | 19 | 05/22/2091 | Managua | NCA | Right | Right | 6' 5" | 200 lbs | - |
| Sanborn, Tyler | SP | San Francisco (Rk+) Giants | 22 | 11/17/2088 | Millville | USA | Left | Left | 5' 10" | 165 lbs | - |
| Sanchez, Jose | RP | Danville Braves | 18 | 01/05/2093 | Managua | NCA | Right | Right | 6' 2" | 180 lbs | - |
| Sanchez, Leon | RP | San Diego (Rk+) Padres | 19 | 06/06/2091 | Mexico City | MEX | Right | Right | 5' 9" | 155 lbs | - |
| Sanders, Oliver | CF | Johnson City Cardinals | 22 | 05/28/2088 | Madison | USA | Right | Right | 6' 0" | 180 lbs | - |
| Sandoval, Antonio | C | Boston (Rk+) Red Sox | 20 | 02/26/2091 | San Cristóbal | DOM | Right | Right | 6' 4" | 205 lbs | - |
| Sands, Jessie | RP | Bristol Pirates | 20 | 05/07/2090 | Dearborn | USA | Right | Right | 6' 4" | 200 lbs | - |
| Santiago, Alexis | 3B | Danville Braves | 20 | 06/01/2090 | Villa del Rosario | VEN | Right | Right | 6' 3" | 195 lbs | - |
| Santiago, Mario | SP | Danville Braves | 20 | 04/06/2090 | Valencia | VEN | Right | Right | 6' 2" | 175 lbs | - |
| Santos, John | RF | Bluefield Blue Jays | 19 | 12/24/2091 | La Romana | DOM | Right | Left | 6' 1" | 195 lbs | - |
| Sauceda, Ivan | C | Burlington Royals | 20 | 08/29/2090 | Santo Domingo | DOM | Right | Right | 6' 4" | 200 lbs | - |
| Saucedo, Franklin | 3B | Burlington Royals | 20 | 08/15/2090 | Boca Chica | DOM | Right | Right | 6' 0" | 200 lbs | - |
| Schrock, John | SS | San Diego (Rk+) Padres | 23 | 01/16/2088 | Los Angeles | USA | Left | Right | 6' 1" | 200 lbs | - |
| Schrupp, Garrett | RP | Free Agent | 26 | 10/20/2084 | Lakewood Park | USA | Left | Left | 6' 0" | 190 lbs | - |
| Schwartz, Brian | SP | Greeneville Astros | 20 | 09/06/2090 | Santa Clara | USA | Left | Left | 6' 3" | 185 lbs | - |
| Shelton, Matthew | CF | Baltimore (Rk+) Orioles | 20 | 02/03/2091 | Plymouth | USA | Right | Right | 6' 2" | 170 lbs | - |
| Sherman, Mike | 1B | Greeneville Astros | 20 | 09/10/2090 | San Diego | USA | Right | Right | 6' 1" | 190 lbs | - |
| Shields, John | RF | Burlington Royals | 22 | 02/08/2089 | Gifford | USA | Right | Right | 6' 2" | 185 lbs | - |
| Shore, Sean | CF | Bristol Pirates | 19 | 07/13/2091 | Phoenix | USA | Right | Right | 6' 0" | 185 lbs | - |
| Silva, Lorenzo | SS | Bluefield Blue Jays | 19 | 12/09/2091 | Villa Jaragua | DOM | Right | Right | 6' 1" | 165 lbs | - |
| Simpson, Danny | CF | Bluefield Blue Jays | 22 | 11/04/2088 | Ennis | USA | Left | Left | 6' 1" | 185 lbs | - |
| Slemp, Chris | 2B | San Francisco (Rk+) Giants | 21 | 10/10/2089 | Waukegan | USA | Right | Right | 5' 10" | 170 lbs | - |
| Sloan, Steve | LF | Johnson City Cardinals | 23 | 12/15/2087 | Los Angeles | USA | Left | Left | 6' 2" | 205 lbs | - |
| Smirnov, Mike | RP | Baltimore (Rk+) Orioles | 25 | 11/12/2085 | Hebron | USA | Right | Right | 6' 3" | 205 lbs | - |
| Smolak, Tyler | SP | Johnson City Cardinals | 19 | 07/14/2091 | San Jose | USA | Left | Left | 6' 4" | 185 lbs | - |
| Soler, Alfredo | SP | Bristol Pirates | 18 | 04/13/2092 | San Cristóbal | DOM | Right | Left | 6' 0" | 165 lbs | - |
| Sosa, David | LF | Pulaski Yankees | 20 | 06/18/2090 | Cúa | VEN | Right | Right | 6' 2" | 200 lbs | - |
| Souza, C.J. | RF | San Diego (Rk+) Padres | 19 | 11/12/2091 | Pembroke Pines | USA | Left | Right | 6' 4" | 200 lbs | - |
| Stanisz, Jason | LF | Johnson City Cardinals | 25 | 01/09/2086 | Danvers | USA | Left | Left | 6' 2" | 200 lbs | - |
| Stringfellow, Phil | CF | Johnson City Cardinals | 21 | 03/10/2090 | Brooklyn | USA | Right | Right | 6' 1" | 165 lbs | - |
| Stroud, Justin | SS | Baltimore (Rk+) Orioles | 21 | 08/18/2089 | Los Angeles | USA | Left | Right | 6' 2" | 190 lbs | - |
| Stufi, Giomar | SP | Bristol Pirates | 20 | 09/18/2090 | Bologna | ITA | Right | Right | 6' 4" | 190 lbs | - |
| Suzuki, Itsuto | RF | Greeneville Astros | 25 | 01/09/2086 | Kuki | JPN | Right | Left | 6' 2" | 200 lbs | - |
