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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sadler, Dan | SP | Frederick Keys | 23 | 03/06/2086 | Holyoke | USA | Right | Right | 5' 10" | 175 lbs | - |
| Salazar, Javier | RP | Free Agent | 29 | 01/30/2080 | Puerto la Cruz | VEN | Right | Right | 5' 10" | 185 lbs | - |
| Samels, Logan | RP | Carolina Mudcats | 24 | 04/30/2085 | Tucson | USA | Right | Right | 6' 1" | 190 lbs | - |
| Sanchez, Johnny | 3B | Winston-Salem Dash | 23 | 10/02/2085 | Santiago | DOM | Right | Right | 6' 4" | 200 lbs | - |
| Sanchez, Jose | RF | Frederick Keys | 27 | 03/23/2082 | Yecuatla | MEX | Switch | Right | 5' 10" | 185 lbs | - |
| Sanchez, Mike | RP | Wilmington Blue Rocks | 25 | 10/31/2083 | Barahona | DOM | Right | Right | 5' 11" | 185 lbs | - |
| Santana, Jose | LF | Potomac Nationals | 22 | 08/02/2086 | Santo Domingo | DOM | Left | Left | 6' 1" | 200 lbs | - |
| Sauer, Joe | LF | Lynchburg Hillcats | 23 | 09/14/2085 | North Salt Lake | USA | Right | Right | 6' 0" | 200 lbs | - |
| Schelling, Gerbrand | SP | Carolina Mudcats | 23 | 04/10/2086 | Tera Kora | ANT | Right | Right | 6' 3" | 180 lbs | - |
| Schilling, Mike | CF | Frederick Keys | 25 | 06/19/2084 | San Francisco | USA | Right | Right | 6' 0" | 190 lbs | - |
| Schneider, Danny | RF | Winston-Salem Dash | 24 | 09/09/2084 | Washington Township | USA | Left | Left | 6' 5" | 205 lbs | - |
| Schroeder, Alan | C | Potomac Nationals | 23 | 09/17/2085 | Temple Hills | USA | Switch | Right | 6' 2" | 200 lbs | - |
| Scott, Aaron | SP | Myrtle Beach Pelicans | 24 | 02/20/2085 | New York | USA | Right | Right | 6' 7" | 200 lbs | - |
| Scott, Justin | C | Free Agent | 24 | 11/06/2084 | Tacoma | USA | Right | Right | 6' 0" | 195 lbs | - |
| Serrano, John | RF | Myrtle Beach Pelicans | 24 | 01/04/2085 | Tyler | USA | Right | Right | 6' 4" | 205 lbs | - |
| Servin, Ernie | RP | Free Agent | 25 | 12/19/2083 | San Cristóbal | DOM | Right | Right | 6' 4" | 205 lbs | - |
| Shearer, Mike | SP | Salem Red Sox | 20 | 01/09/2089 | Foster City | USA | Left | Right | 6' 7" | 200 lbs | - |
| Sheerer, Dillon | SP | Free Agent | 27 | 01/31/2082 | Natchitoches | USA | Right | Right | 6' 4" | 200 lbs | - |
| Shepard, Nick | SS | Salem Red Sox | 23 | 02/04/2086 | Pleasant Run Farm | USA | Right | Right | 6' 0" | 185 lbs | - |
| Silva, Alfredo | SP | Winston-Salem Dash | 24 | 03/16/2085 | Santo Domingo | DOM | Right | Right | 6' 1" | 195 lbs | - |
| Smith, Jamar | SP | Free Agent | 33 | 12/13/2075 | Asheville | USA | Right | Right | 6' 4" | 200 lbs | - |
| Solis, Leonel | RP | Free Agent | 24 | 01/20/2085 | El Limón | VEN | Right | Right | 6' 2" | 190 lbs | - |
| Solis, Willie | RP | Potomac Nationals | 24 | 08/28/2084 | León | MEX | Right | Right | 6' 2" | 190 lbs | - |
| Spalinger, Ryan | CF | Carolina Mudcats | 20 | 08/10/2088 | Racine | USA | Right | Right | 6' 1" | 185 lbs | - |
| Spencer, Amari | RF | Frederick Keys | 23 | 03/09/2086 | Detroit | USA | Switch | Left | 6' 2" | 200 lbs | - |
| Starks, Tim | C | Winston-Salem Dash | 24 | 04/13/2085 | Salt Lake City | USA | Right | Right | 6' 1" | 200 lbs | - |
| Starr, Justin | LF | Free Agent | 25 | 07/25/2083 | Aspen Hill | USA | Right | Right | 6' 3" | 205 lbs | - |
| Steward, Jeff | RP | Frederick Keys | 27 | 04/27/2082 | Apple Valley | USA | Right | Right | 6' 7" | 200 lbs | - |
| Stewart, Eric | CF | Myrtle Beach Pelicans | 27 | 05/15/2082 | Surrey | CAN | Right | Right | 6' 0" | 200 lbs | - |
| Stockman, Matt | 3B | Salem Red Sox | 23 | 10/11/2085 | Lawrenceburg | USA | Switch | Right | 6' 0" | 200 lbs | - |
| Sulla, Rich | SS | Winston-Salem Dash | 25 | 01/01/2084 | Glendale Heights | USA | Right | Right | 6' 2" | 200 lbs | - |
