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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sain, Dan | SP | Staten Island Yankees | 20 | 01/29/2079 | Paterson | USA | Right | Right | 6' 2" | 185 lbs | - |
| Salas, Angelo | SP | West Virginia Black Bears | 19 | 10/02/2079 | Tenares | DOM | Right | Right | 6' 4" | 190 lbs | - |
| Salas, Tony | RP | Hudson Valley Renegades | 22 | 10/24/2076 | Barcelona | VEN | Right | Right | 5' 10" | 165 lbs | - |
| Sanchez, Luis | RP | Brooklyn Cyclones | 23 | 03/22/2076 | La Romana | DOM | Switch | Right | 5' 9" | 170 lbs | - |
| Sandino, Felix | RF | Mahoning Valley Scrappers | 22 | 04/23/2076 | Cotuí | DOM | Right | Left | 6' 2" | 180 lbs | - |
| Sanford, Mike | SP | Hudson Valley Renegades | 20 | 05/19/2078 | Santa Rosa | USA | Left | Left | 6' 2" | 190 lbs | - |
| Sangster, John | C | Connecticut Tigers | 23 | 03/28/2076 | Denver | USA | Left | Right | 5' 10" | 180 lbs | - |
| Santiago, Danny | RF | Aberdeen Ironbirds | 20 | 01/15/2079 | Postrer Río | DOM | Right | Left | 6' 3" | 195 lbs | - |
| Santiago, Jose | SP | Aberdeen Ironbirds | 18 | 11/13/2080 | Weymouth | USA | Right | Right | 6' 2" | 175 lbs | - |
| Schmidt, Bobby | C | Hudson Valley Renegades | 21 | 01/23/2078 | Idaho Falls | USA | Right | Right | 6' 3" | 190 lbs | - |
| Schoolcraft, Jared | 1B | Vermont Lake Monsters | 22 | 09/11/2076 | Springfield | USA | Left | Left | 6' 2" | 215 lbs | - |
| Schulz, Nick | SS | West Virginia Black Bears | 22 | 11/19/2076 | Joliet | USA | Right | Right | 6' 0" | 180 lbs | - |
| Sears, Joe | C | Hudson Valley Renegades | 21 | 11/04/2077 | Jacksonville | USA | Right | Right | 6' 0" | 190 lbs | - |
| Setters, Craig | C | State College Spikes | 22 | 10/30/2076 | Rocky Mount | USA | Right | Right | 6' 4" | 210 lbs | - |
| Shapiro, Chris | SS | Connecticut Tigers | 20 | 05/29/2078 | Hollywood | USA | Switch | Right | 6' 6" | 185 lbs | - |
| Shorey, John | SP | Williamsport Crosscutters | 23 | 05/13/2075 | South Milwaukee | USA | Left | Right | 6' 8" | 200 lbs | - |
| Sierra, Joel | CF | Lowell Spinners | 20 | 10/08/2078 | San José de Ocoa | DOM | Right | Right | 5' 10" | 165 lbs | - |
| Sierra, Mario | CF | West Virginia Black Bears | 22 | 08/29/2076 | Puerto Plata | DOM | Right | Right | 6' 2" | 175 lbs | - |
| Siller, Alex | 1B | Vermont Lake Monsters | 23 | 06/20/2075 | Caguas | PUR | Right | Right | 6' 6" | 220 lbs | - |
| Slaughter, Jarred | C | Lowell Spinners | 22 | 08/30/2076 | Arlington | USA | Right | Right | 6' 2" | 200 lbs | - |
| Smeets, Davey | SP | State College Spikes | 20 | 06/26/2078 | Kralendijk | ANT | Right | Right | 6' 4" | 195 lbs | - |
| Sneed, Phil | 3B | Mahoning Valley Scrappers | 22 | 05/18/2076 | Scotch Plains | USA | Right | Right | 6' 3" | 200 lbs | - |
| Soto, Gil | RP | Batavia Muckdogs | 22 | 05/22/2076 | Ciudad Bolívar | VEN | Left | Right | 6' 2" | 195 lbs | - |
| Spicer, Gaige | SS | Williamsport Crosscutters | 23 | 11/18/2075 | Miami | USA | Right | Right | 6' 0" | 180 lbs | - |
| Steiner, Mike | SS | Tri-City ValleyCats | 23 | 06/02/2075 | Ft. Collins | USA | Right | Right | 6' 4" | 200 lbs | - |
| Stickelman, Craig | RP | Vermont Lake Monsters | 21 | 08/12/2077 | Nashville | USA | Right | Right | 6' 2" | 180 lbs | - |
| Stokes, Trevor | RP | Auburn Doubledays | 21 | 09/26/2077 | Blue Ash | USA | Switch | Right | 6' 0" | 190 lbs | - |
| Struthers, Adam | 3B | West Virginia Black Bears | 18 | 07/29/2080 | Chicago | USA | Right | Right | 6' 1" | 195 lbs | - |
| Suarez, Arturo | C | State College Spikes | 22 | 02/05/2077 | Santiago | DOM | Right | Right | 6' 3" | 200 lbs | - |
| Sweigart, Mike | SP | Williamsport Crosscutters | 24 | 06/09/2074 | East Hanover | USA | Right | Right | 6' 0" | 185 lbs | - |
